This test is one of the components of the Liver Health Panel. Albumin is the most abundant protein in the blood plasma It keeps fluid from leaking out of blood vessels; nourishes tissues; and transports hormones, vitamins, drugs, and ions like calcium throughout the body. Albumin is made in the liver and is extremely sensitive to liver damage. The concentration of albumin drops when the liver is damaged, with kidney disease (nephrotic syndrome), when a person is malnourished, if a person experiences inflammation in the body, or with shock. Albumin increases when a person is dehydrated.